CD52 (Protein | Antibody | cDNA Clone | ELISA Kit)

All CD52 reagents are produced in house and quality controlled, including 1 CD52 Antibody, 52 CD52 Gene, 3 CD52 Lysate, 3 CD52 Protein, 3 CD52 qPCR. All CD52 reagents are ready to use.

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CD52 Background

CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

CD52 References

  • Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.