CTAG2 cDNA ORF Clone in Cloning Vector, Human

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CTAG2 cDNA ORF Clone in Cloning Vector, Human: General Information

Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
543 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human cancer/testis antigen 2.
Plasmid
Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

CTAG2 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CTAG2 cDNA ORF Clone in Cloning Vector, Human: Alternative Names

CAMEL cDNA ORF Clone, Human; CT2 cDNA ORF Clone, Human; CT6.2 cDNA ORF Clone, Human; CT6.2a cDNA ORF Clone, Human; CT6.2b cDNA ORF Clone, Human; ESO2 cDNA ORF Clone, Human; LAGE-1 cDNA ORF Clone, Human; LAGE2B cDNA ORF Clone, Human

CTAG2 Background Information

CAMEL (19 aa) is a tumor-specific protein translated from the LAGE-1 gene in an alternative open reading frame (ORF) starting at a second ATG start codon located 4 bp downstream of the first ATG start site. LAGE-1 shows 94% homology to tumor Ag NY-ESO-1 and both genes are located on chromosome Xp28. The LAGE-1 and NY-ESO-1 genes are frequently coexpressed in a wide variety of tumors, like melanoma, breast carcinoma, prostate and bladder cancers, but silent in normal tissues except for testis.
Full Name
cancer/testis antigen 2
References
  • Slager E H, van der Minne C E, Krüse M, et al. Identification of multiple HLA-DR-restricted epitopes of the tumor-associated antigen CAMEL by CD4+ Th1/Th2 lymphocytes[J]. The Journal of Immunology, 2004, 172(8): 5095-5102.

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