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Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-His Marqueur

Fiche techniqueCommentairesProduits apparentésProtocoles
Human SRC Informations sur les produits clonés de cDNA
Gene_bank_ref_id:NM_005417.3
Taille du ADNc:1611bp
Description du ADNc:Full length Clone DNA of Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) with N terminal His tag.
Synonyme du gène:ASV, SRC1, c-SRC, p60-Src, SRC
Espèces:Human
Vecteur:pCMV3-N-His
Plasmid:
Site de restriction:
Séquence du marqueur:His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
Description de la séquence:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Stockage:The lyophilized plasmid can be stored at room temperature for three months.
His Tag Info

A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.

Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.

Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-His Marqueur on other vectors
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-GFPSpark MarqueurHG10755-ACGCHF290
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-OFPSpark MarqueurHG10755-ACRCHF290
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-GFPSpark MarqueurHG10755-ANGCHF290
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-OFPSpark MarqueurHG10755-ANRCHF290
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-Flag MarqueurHG10755-CFCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-His MarqueurHG10755-CHCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-Myc MarqueurHG10755-CMCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, C-HA MarqueurHG10755-CYCHF260
Humain SRC/Proto-oncogene c-Src Gène ADNc clone le vecteur de clonageHG10755-MCHF90
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-Flag MarqueurHG10755-NFCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-His MarqueurHG10755-NHCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-Myc MarqueurHG10755-NMCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF clone, N-HA MarqueurHG10755-NYCHF260
Humain SRC/Proto-oncogene c-Src expression plasmide de Gène l'ADNc ORF cloneHG10755-UTCHF260
 En savoir plus sur les vecteurs d'expression
Product nameProduct name
Fond

Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.

Références
  • Juan Ma. et al., 2003, Neuroscience Letters. 348 (3): 185-189.
  • Czernilofsky AP. et al., 1980, Nature. 287: 198-203.
  • Beischlag TV. et al., 2002, Molecular and cellular biology. 22 (12): 4319-33.
  • Size / Price
    Catalogue : HG10755-NH
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    Disponibilité2-3 weeks
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