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IL-3 Anticorps, Anticorps polyclonaux de lapin, Antigen Affinity Purified

  • IL-3 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Fiche techniqueCommentairesProduits apparentésProtocoles
Rat IL3 Informations sur les produits relatifs aux anticorps
Immunogène:Recombinant Rat IL-3 protein (Catalog#80235-R08B)
Clone ID:
Type d’Ig:Rabbit IgG
Concentration:
Endotoxine:
Tampon:0.2 μm filtered solution in PBS with 5% trehalose
Préparation d'anticorps:Produced in rabbits immunized with purified, recombinant Rat IL-3 (rR IL-3; Catalog#80235-R08B; NP_113701.1; Met1-Cys169). IL-3 specific IgG was purified by Rat IL-3 affinity chromatography.
Rat IL3 Antibody IHC Application Image
IL-3 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Caption:
Immunochemical staining of rat IL3 in rat spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
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                IL3/IL-3/Interleukin-3 Fond

                IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

                Rat IL3/IL-3/Interleukin-3 Références
              • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
              • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
              • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.
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                Size / Price
                Catalogue : 80235-RP02-200
                Prix catalogue : 
                Prix :      (You Save: )

                Datasheet & Documentation

                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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