Commande rapide

IL6 / Interleukin-6 Anticorps, Anticorps polyclonaux de lapin, Antigen Affinity Purified

  • IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Fiche techniqueCommentairesProduits apparentésProtocoles
Rhésus IL6 Informations sur les produits relatifs aux anticorps
Immunogène:Recombinant Rhesus IL6 / Interleukin-6 protein (Catalog#90197-CNAE)
Clone ID:
Type d’Ig:Rabbit IgG
Concentration:
Endotoxine:
Tampon:0.2 μm filtered solution in PBS
Préparation d'anticorps:Produced in rabbits immunized with purified, recombinant Rhesus IL6 / Interleukin-6 (Catalog#90197-CNAE; NP_001036198.2; Pro29-Met212). IL6 / Interleukin-6 specific IgG was purified by Rhesus IL6 / Interleukin-6 affinity chromatography.
Rhésus IL6 Antibody IHC Application Image
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Cliquer pour agrandir l’image]
Caption:
Immunochemical staining of cynomolgus IL6 in human liver with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Cliquer pour agrandir l’image]
Caption:
Immunochemical staining of cynomolgus IL6 in human spleen with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Cliquer pour agrandir l’image]
Caption:
Immunochemical staining of cynomolgus IL6 in human tonsil with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
Other IL6 Antibody Products

Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

Lane A: NIH3T3 Whole Cell Lysate

Lane B: Hela Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size:15 kDa

Observed band size:17 kDa

IL6/IL-6/Interleukin-6 Fond

Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Rhésus IL6/IL-6/Interleukin-6 Références
  • Heinrich PC. et al. (2003). Principles of interleukin-6-type cytokine signalling and its regulation. Biochem J. 374: 1-20.
  • Rose-John S, et al. (2007) The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets. 11(5): 613-24.
  • Dinh W, et al. (2009) Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. Cardiovasc Diabetol. 8:58.
  • Product nameProduct name
    Size / Price
    Catalogue : 90197-RP02-50
    Prix catalogue : 
    Prix :      (You Save: )
    Taille :
    50 µg
    100 µg
    200 µg
    Quantité :+-
    DisponibilitéIn Stock
    Ajouter au panierBulk Discount Requiry

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Veuillez noter : Tous les produits sont « DESTINÉS À LA RECHERCHE UNIQUEMENT ET NE SONT PAS PRÉVUS POUR ÊTRE UTILISÉS À DES FINS DE DIAGNOSTIC OU THÉRAPEUTIQUES »