LDOC1 cDNA ORF Clone in Cloning Vector, Human


LDOC1 cDNA ORF Clone in Cloning Vector, Human: General Information

NCBI Ref Seq
RefSeq ORF Size
441 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Full length Clone DNA of Human leucine zipper, down-regulated in cancer 1.
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.

LDOC1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

LDOC1 cDNA ORF Clone in Cloning Vector, Human: Alternative Names

42070 cDNA ORF Clone, Human; BCUR1 cDNA ORF Clone, Human; Mart7 cDNA ORF Clone, Human

LDOC1 Background Information

LDOC1 was first identified as a gene encoding a leucine zipper protein whose expression was decreased in a series of pancreatic and gastric cancer cell lines. LDOC1 gene is a known regulator of nuclear factor mediated pathway to apoptosis through inhibition of nuclear factor kappa B (NF-kappaB). Upregulation of LDOC1 in HIBEC increases the expression of NF-kappaB, which may promote the activation of IL-2 and TNF-alpha secretion and inhibit cell apoptosis. The silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.
Full Name
leucine zipper, down-regulated in cancer 1
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