Anti-Peroxiredoxin 5 Antibody

Cat: 50551-RP01
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Anti-Peroxiredoxin 5 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Peroxiredoxin 5 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse Peroxiredoxin 5
Immunogen
Recombinant Mouse Peroxiredoxin 5 / PRDX5 protein (Catalog#50551-M07E)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse Peroxiredoxin 5 / PRDX5 (rM Peroxiredoxin 5 / PRDX5; Catalog#50551-M07E; P99029-1; Met 49-Leu 210). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Peroxiredoxin 5 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Peroxiredoxin 5 Antibody Alternative Names
Anti-AOEB166 Antibody;Anti-AOPP Antibody;Anti-Pmp20 Antibody;Anti-Prdx6 Antibody;Anti-PrxV Antibody
Peroxiredoxin 5 Background Information

Peroxiredoxin-5, also known as Alu corepressor 1, Antioxidant enzyme B166, Liver tissue 2D-page spot 71B, Peroxisomal antioxidant enzyme, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5 and ACR1, is cytoplasm protein which belongs to the?peroxiredoxin 2 family. Peroxiredoxin-5 / PRDX5 reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-5 / PRDX5 is involved in intracellular redox signaling. The Peroxiredoxins / Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

Full Name
peroxiredoxin 5
References
  • Seo M.S., et al., 2000, J. Biol. Chem. 275: 20346-54.
  • Declercq J.-P., et al., 2001, J. Mol. Biol. 311:751-9.
  • Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90.
  • Schremmer,B. et al., 2007, Subcell Biochem. 44 :317-44.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Peroxiredoxin 5 Antibody Rabbit Polyclonal ELISA 50551-T16
    Anti-Peroxiredoxin 5 Antibody Rabbit Monoclonal ELISA 11263-R125
    Anti-Peroxiredoxin 5 Antibody Rabbit Polyclonal WB,ELISA 11263-RP01
    Anti-Peroxiredoxin 5 Antibody Rabbit Monoclonal WB,ICC/IF,IF,IP 11263-R002
    Anti-Peroxiredoxin 5 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 11263-RP02
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