|Fiche technique||Commentaires||Produits apparentés||Protocoles|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat KLRC1 ORF mammalian expression plasmid, C-GFPSpark tag||RG80370-ACG|
|Rat KLRC1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80370-ACR|
|Rat KLRC1 ORF mammalian expression plasmid, C-Flag tag||RG80370-CF|
|Rat KLRC1 ORF mammalian expression plasmid, C-His tag||RG80370-CH|
|Rat KLRC1 ORF mammalian expression plasmid, C-Myc tag||RG80370-CM|
|Rat KLRC1 ORF mammalian expression plasmid, C-HA tag||RG80370-CY|
|Rat KLRC1 Gene cDNA clone plasmid||RG80370-G|
|Rat KLRC1 ORF mammalian expression plasmid, N-Flag tag||RG80370-NF|
|Rat KLRC1 ORF mammalian expression plasmid, N-His tag||RG80370-NH|
|Rat KLRC1 ORF mammalian expression plasmid, N-Myc tag||RG80370-NM|
|Rat KLRC1 ORF mammalian expression plasmid, N-HA tag||RG80370-NY|
|Rat KLRC1 natural ORF mammalian expression plasmid||RG80370-UT|
|En savoir plus sur les vecteurs d'expression|
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this fmaily are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.