Anti-Serpinb3c Antibody


Anti-Serpinb3c Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-Serpinb3c Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse Serpinb3c
Recombinant Mouse Serpinb3c protein (Catalog#50625-M08B)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Serpinb3c (rM Serpinb3c; Catalog#50625-M08B; NP_958751.2; Met 1-Pro 386).
Monoclonal Rabbit IgG Clone #013
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Serpinb3c Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Serpinb3c Antibody: Alternative Names

Anti-1110001H02Rik Antibody; Anti-1110013A16Rik Antibody; Anti-Scca2 Antibody; Anti-Serpinb3c Antibody; Anti-Serpinb4 Antibody

Serpinb3c Background Information

Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1 serpins have been identified.
Mouse SerpinB3, also known as Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA and SCCA1, is a cytoplasm protein which belongs to theserpin family and Ov-serpin subfamily. SerpinB3 may act as a protease inhibitor to modulate the host immune response against tumor cells. Mouse SerpinB3a and SerpinB3b, but not Serpinb3c, are functional, inhibiting both serine and cysteine proteinases with different inhibitory profiles due to the difference of two amino acids in their reactive site loops. SerpinB3a is ubiquitously expressed in most tissues, whereas expression of SerpinB3b is limited to keratinocytes. SerpinB3a and SerpinB3b may play different roles by inhibiting intrinsic or extrinsic proteinases with different expression distributions and different inhibitory profiles.
Full Name
serine (or cysteine) peptidase inhibitor, clade B, member 3C
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  • Przygodzka, P. et al., 2010, BMC Cell Biol. 11: 30. 
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