Anti-TNF-alpha Antibody


Anti-TNF-alpha Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-TNF-alpha Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse TNF-alpha
Has cross-reactivity in ELISA with
Human TNFa
Recombinant Mouse TNF-alpha / TNFa protein (Catalog#50349-MNAE)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNF-alpha / TNFa (rM TNF-alpha / TNFa; Catalog#50349-MNAE; NP_038721.1; Leu 80-Leu 235).
Monoclonal Rabbit IgG Clone #009
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-TNF-alpha Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-TNF-alpha Antibody: Alternative Names

Anti-DIF Antibody; Anti-TNF-a Antibody; Anti-TNF-alpha Antibody; Anti-Tnfa Antibody; Anti-TNFalpha Antibody; Anti-Tnfsf1a Antibody; Anti-TNFSF2 Antibody

TNF-alpha Background Information

Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD12a; p55/6) and TNF-R2 (TNF receptor type 2; CD12b; p75/8), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
Full Name
tumor necrosis factor
Research Areas
  • Hector J, et al. (2007) TNF-alpha alters visfatin and adiponectin levels in human fat. Horm Metab Res. 39(4): 250-5.
  • Berthold-Losleben M, et al. (2008) The TNF-alpha System: Functional Aspects in Depression, Narcolepsy and Psychopharmacology. Curr Neuropharmacol. 6(3): 193-202.
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