FCRN/FCGRT cDNA Clone: Expression and Clone Vector / Plasmid

FCRN/FCGRT cDNA / Gene Overview

FCGRT gene / cDNA is a protein-coding gene which located on 19q13.33. The FCGRT gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.116 organisms have orthologs with human gene FCGRT.

FCRN/FCGRT cDNA / Gene Function

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

FCRN/FCGRT cDNA / Gene Sequence

LOCUS
LOCUS NM_001136019 1893 bp mRNA linear PRI 24-JUN-2018
DEFINITION
Homo sapiens Fc fragment of IgG receptor and transporter (FCGRT), transcript variant 1, mRNA.
ACCESSION
NM_001136019
VERSION
NM_001136019.2

This sequence information is just for reference only.

FCRN/FCGRT Family & Reagents

FCRN/FCGRT Gene family reagents (C1-set domain containing)

Approved Symbol Reagent list
AZGP1
CD1B
HHLA2
MICB
SIRPA
TAPBP
Approved Symbol Reagent list
B2M
CD1D
MICA
NCR3LG1
SIRPG
   

FCRN/FCGRT cDNA / Gene Alias

  • alpha-chain
  • FCRN
  • heavy chain of the major histocompatibility complex class I-like Fc receptor
  • transmembrane alpha chain of the neonatal receptor

FCRN/FCGRT cDNA / Gene Expression

Ubiquitous expression in duodenum (RPKM 99.0), small intestine (RPKM 98.5) and 25 other tissues