Viral Antigens

Reagents for Serological Analysis of SARS-COV-2

Sino Biological is dedicated to supporting the study of infectious diseases. Throughout the years, the company has built the world largest bank of recombinant viral antigens. This unique portfolio includes the one-of-a-kind coronavirus catalog, a huge collection of infleunza antigens from over 100 strains, and many other hard-to-find viral proteins such as RSV, Ebola, and Cytomegalovirus. These reagents are specifically developed to help vaccine research and drug development.

Human Coronavirus Antigens

Research Reagents by Virus Types

Research Reagents by Viral Antigens

Viral Molecules
Viral Molecules
Receptors & Infection related
Viral Molecules
Receptors & Infection related
Viral Molecules
Viral Molecules
Receptors & Infection related
Viral Molecules
Viral Molecules
Viral Molecules
Viral Molecules
Viral Molecules
Viral Molecules
Viral Molecules
Viral Molecules
Receptors & Infection related
Viral Molecules
Viral Molecules
Receptors & Infection related
Viral Molecules
Viral Molecules
Receptors & Infection related
Viral Molecules
Viral Molecules
Receptors & Infection related
 

Information about Viral Antigen Detection

Many of the assay formats used to detect antibodies are also used to detect viral antigens.

SPIA

SPIAs are widely used to detect HBV antigens (HBsAg and HBeAg) and HIV p24 antigen.
   

Immunofluorescence

Direct immunofluorescent assays (DFA) for the detection of viral antigens in infected cells are widely used for the diagnosis of respiratory virus infections and herpetic skin lesions. DFA can be performed on many cellular sample types, especially nasopharyngeal washes, aspirates or swabs, bronchoalveloar lavage, skin and mucosal lesions, PBL and tissue biopsies.The advantage of this technique is that it is quick and easy to perform and results can be available in a short period of time. However, it requires a skilled operator and a flourescent microscope. It is a difficult procedure to scale up and non-specific binding can make interpretation of results difficult.
   

Lateral flow immunochromatography

IC assays are available for rotavirus but are most widely used for the detection of influenza A and B and RSV.
   

Latex agglutination


Latex beads coated with virus-specific antibodies have been used for the detection of viral antigen, such as for rotavirus and enteric adenovirus in stools of infants, and more recently for norovirus
   

Electron microscopy

It allows direct visualisation of the virus, but requires high viral titres to be detected.
 

Viral Antigen Research Related Information

 

Viral Antigen Research Reference

• Tony Mazzulli, in Principles and Practice of Pediatric Infectious Diseases (Fifth Edition), 2018

• David R. Peaper, Marie Louise Landry, in Handbook of Clinical Neurology, 2014

• Stephen N.J. Korsman MMed FCPath, ... Wolfgang Preiser MRCPath, in Virology, 2012