KIR2DL5 Proteins, cDNA Clones Research Reagents

KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A, also known as CD158F; KIR2DL5; KIR2DL5.1; KIR2DL5.3), located on 19p13.3, is a Protein Coding gene. The gene produces a 40678 Da protein composed of 375 amino acids. The encoded protein belongs to the immunoglobulin superfamily. KIR2DL5 is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA. The related pathways of KIR2DL5A include the Immune response Role of DAP12 receptors in NK cells and Allograft rejection.
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KIR2DL5 General Information

KIR2DL5 Protein (1)

Species

    KIR2DL5 cDNA Clone (13)

    NM_020535.3

    In cloning vector

    In cloning vector

    In expression vector

    untagged

    C-GFPSpark C-OFPSpark C-DDK tag N-DDK tag C-His tag N-His tag C-HA tag N-HA tag C-Myc N-Myc

    In lentiviral vector

    C-GFPSpark

    KIR2DL5 Lysate (1)

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      KIR2DL5 Background

      KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A) is a Protein Coding gene. The encoded protein belongs to the immunoglobulin superfamily. The most recently described member of the KIR family, KIR2DL5, is represented in human populations by at least four gene variants, whose exons differ by two to eight nucleotides. KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA. KIR2DL5 is encoded by two paralogous genes displaying copy number variation and allelic polymorphism-KIR2DL5A and KIR2DL5B. Functional polymorphisms in both its promoter and its coding regions are critical for understanding the KIR2DL5 role in immunity and its importance for human health.

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