CD23 Gene Sequence, Family, Fuction and Expression Information

CD23 cDNA / Gene Overview

FCER2 gene / cDNA is a protein-coding gene which located on 19p13.2. The FCER2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.105 organisms have orthologs with human gene FCER2.

CD23 cDNA / Gene Function

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

CD23 cDNA / Gene Sequence

LOCUS
LOCUS NM_002002 1620 bp mRNA linear PRI 24-JUN-2018
DEFINITION
Homo sapiens Fc fragment of IgE receptor II (FCER2), transcript variant 1, mRNA.
ACCESSION
NM_002002
VERSION
NM_002002.4

This sequence information is just for reference only.

CD23 Family & Reagents

CD23 Gene family reagents (CD molecules)

Approved Symbol Reagent list
CDH5
CSF3R
CD200
CDH1
CLEC4D
GP1BA
CD99
PDGFRB
JAG1
ENG
Approved Symbol Reagent list
CD8A
L1CAM
TFRC
ICAM1
CD53
CD34
CD1B
ICOSLG
BST1
CD180

CD23 Gene family reagents (C-type lectin domain containing)

Approved Symbol Reagent list
COLEC10
CLEC6A
CLEC4F
CD93
CLEC2B
CLEC2D
CLEC4A
SELE
SELL
CLEC1A
Approved Symbol Reagent list
THBD
CLEC1B
CLEC4E
COLEC11
CD302
KLRC1
REG3A
OLR1
CHODL
CLEC10A

CD23 cDNA / Gene Alias

  • CD23
  • CLEC4J
  • Fc epsilon receptor II

CD23 cDNA / Gene Expression

Biased expression in spleen (RPKM 20.9), lymph node (RPKM 16.3) and 4 other tissues